as an mcu player, no comic knowledge is necessary. the movies are their own entity, which is why they're listed as their own verse in the marvel world. some of the origin stories are pretty different, or the characterizations are wildly different as well. as long as you say you're playing from mcu/netflix and not comics, no one will care. i play from the movies and don't read comics. that's sort of the point of watching the movies, to be able to get into that world and those characters without 20 years of comics behind it.
but watch the series entirely, or up to the canon point you want to play. especially with the netflix shows, things can change pretty drastically, so if you're playing matt s2 and you've only seen s1, you really do need to catch up, because his personality changes quite a bit (clearly just an example). just make sure you actually watch it and i promise you, no one will care.
or, to be more fair, some people will care, but they won't have any ground to really bitch because they're two separate verses and as long as you're up to speed on your char's canon point, they're just being grumpy assholes.
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but watch the series entirely, or up to the canon point you want to play. especially with the netflix shows, things can change pretty drastically, so if you're playing matt s2 and you've only seen s1, you really do need to catch up, because his personality changes quite a bit (clearly just an example). just make sure you actually watch it and i promise you, no one will care.
or, to be more fair, some people will care, but they won't have any ground to really bitch because they're two separate verses and as long as you're up to speed on your char's canon point, they're just being grumpy assholes.